James D. Watson
67 quotes
Biography
James Dewey Watson was an American molecular biologist, geneticist, and zoologist. In 1953, he and Francis Crick co-authored an academic paper in Nature proposing the double helix structure of the DNA molecule, building on research by Rosalind Franklin and Raymond Gosling.
"The ever quickening advances of science made possible by the success of the Human Genome Project will also soon let us see the essences of mental disease. Only after we understand them at the genetic level can we rationally seek out appropriate therapies for such illnesses as schizophrenia and bipolar disease."
"Every time you understand something, religion becomes less likely. Only with the discovery of the double helix and the ensuing genetic revolution have we had grounds for thinking that the powers held traditionally to be the exclusive property of the gods might one day be ours. . . ."
"People say we are playing God. My answer is: If we don't play God, who will?"
"The brain is the last and grandest biological frontier, the most complex thing we have yet discovered in our universe. It contains hundreds of billions of cells interlinked through trillions of connections. The brain boggles the mind."
"There is only one science, physics: everything else is social work."
"Moving forward will not be for the faint of heart. But if the next century witnesses failure, let it be because our science is not yet up to the job, not because we don't have the courage to make less random the sometimes most unfair courses of human evolution."
"To succeed in science, you have to avoid dumb people (here I was still following Luria's example). Now that might sound inexcusably flip, but the fact is that you must always turn to people who are brighter than yourself."
"To make a huge success, a scientist must be prepared to get into deep trouble. Sometime or another, someone will tell you that you are not ready to do something. … If you are going to make a big jump in science, you will very likely be unqualified to succeed by definition. The truth, however, won't save you from criticism. Your very willingness to take on a very big goal will offend some people who will think that you are too big for your britches and crazy to boot."
"Be sure you have someone up your sleeve who will save you when you find yourself in deep s—."
"Never do anything that bores you. My experience in science is that someone is always telling to do something that leaves you flat. Bad idea. I'm not good enough to do something I dislike. In fact, I find it hard enough to do something that I like. … Constantly exposing your ideas to informed criticism is very important, and I would venture to say that one reason both of our chief competitors failed to reach the Double Helix before us was that each was effectively very isolated."
"Whenever you interview fat people, you feel bad, because you know you're not going to hire them."
"No one may have the guts to say this, but if we could make better human beings by knowing how to add genes, why shouldn't we?"
"I just can’t sit while people are saying nonsense in a meeting without saying it’s nonsense."
"People say it would be terrible if we made all girls pretty. I think it would be great."
"Never be the brightest person in the room. … We're all imperfect."
"Science Ph.D. students have effectively become serfs. And who would become a serf when you can work for Goldman Sachs and get paid $300,000 a year to become a serf? Why drive a Chevy when you can drive a BMW — and now you're condemned to driving a car from Malaysia or something. Life should be fun."
"Should you be allowed to make an anti-Semitic remark? Yes, because some anti-Semitism is justified. Just like some anti-Irish feeling is justified. If you can't be criticized, that's very dangerous. The whole Larry Summers thing, to say that men are a bit strange and their strangest quality is their ability to understand mathematics -- you're not supposed to even think it."
"I turned against the left wing because they don't like genetics, because genetics implies that sometimes in life we fail because we have bad genes. They want all failure in life to be due to the evil system."
"If you could make people with ten-point-higher IQs, we'd probably have fewer wars."
"Do things as soon as you can. If a decision needs to be made, make it. It gives you more time to change your mind."
"No one really wants to admit I exist."
"Crick, however, was right. Our discovery put an end to a debate as old as the human species: Does life have some magical, mystical essence, or is it, like any chemical reaction carried out in a science class, the product of normal physical and chemical processes? Is there something divine at the heart of a cell that brings it to life? The double helix answer that question with a definitive No."
"That is why the double helix was so important. It brought the Enlightenment revolution in materialistic thinking into the cell. The intellectual journey that had begun with Copernicus displacing humans from the center of the universe and continued with Darwin’s insistence that humans are merely modified monkeys had finally focused in on the very essence of life. And there was nothing special about it. The double helix is an elegant structure, but its message is downright prosaic: life is simply a matter of chemistry."
"The discovery of the double helix sounded the death knell for vitalism. Serious scientists, even those religiously inclined, realized that a complete understanding of life would not require the revelation of new laws of nature. Life was just a matter of physics and chemistry, albeit exquisitely organized physics and chemistry. The immediate task ahead would be to figure out how the DNA-encoded script of life went about its work."
"The opposition to GM foods is largely a sociopolitical movement whose arguments, though couched in the language of science, are typically unscientific. Indeed, some of the anti-GM pseudoscience propagated by the media—whether in the interests of sensationalism or out of misguided but well-intentioned concern—would be actually amusing were it not evident that such gibberish is in fact an effective weapon in the propaganda war."