“Life is meaningless, but it also has meaning—or, more accurately, meanings. There is no such thing as the meaning of life. Many different meanings are possible. One can transcend the self and make a positive mark on the lives of others in myriad ways. These include nurturing and teaching the young, caring for the sick, bringing relief to the suffering, improving society, creating great art or literature, and advancing knowledge. We are nonetheless warranted in regretting our cosmic insignificance and the pointlessness of the entire human endeavor. As impressed as (some) humans often are about the significance of humanity’s presence in the cosmos, our absence would have made absolutely no difference to the rest of the universe. We serve no purpose in the cosmos and, although our efforts have some significance here and now, it is seriously limited both spatially and temporally. Even those who think that we ought not to yearn for the greater meaning that is unattainable must recognize the immense tragedy of beings who suffer such existential anxiety over their insignificance. That suffering is indisputably a part of the human predicament.”